Siliconizing Fluid 522 0060011 1875560 9/30/2008. 9/30/2008. Material Safety Data Sheet Product name Manufacturer Product No. MSDS # Validation date Print date In case of emergency Product and company identification Responsible name MSDS Specialist : : : : : : : 1 . CHEMTREC: 800.424.9300 OUTSIDE US: 202.483.7616 Supplier : Thermo Fisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 or 800.874.3723 : Use of Substance/Preparation Refer to the instruction booklet for proper and intended use. Otherwise, contact supplier for specific applications. : Thermo Fisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 800.874.3723 Part of Thermo Fisher Scientific Emergency overview Hazards identification Potential acute health effects Toxic by inhalation. Corrosive to the respiratory system. Toxic if swallowed. May cause burns to mouth, throat and stomach. Inhalation Ingestion Physical state Liquid. DANGER ! WATER-REACTIVE SUBSTANCE. REACTS WITH WATER TO RELEASE FLAMMABLE GAS. REACTS WITH WATER TO RELEASE TOXIC GAS. MAY CAUSE FIRE. MAY BE FATAL IF INHALED. CAUSES RESPIRATORY TRACT, EYE AND SKIN BURNS. HARMFUL IF ABSORBED THROUGH SKIN OR IF SWALLOWED. PROLONGED OR REPEATED CONTACT MAY DRY SKIN AND CAUSE IRRITATION. CONTAINS MATERIAL THAT CAN CAUSE TARGET ORGAN DAMAGE. POSSIBLE CANCER HAZARD - CONTAINS MATERIAL WHICH MAY CAUSE CANCER, BASED ON ANIMAL DATA. Contact with water liberates toxic, extremely flammable gas. Toxic by inhalation, in contact with skin and if swallowed. Corrosive to the eyes, skin and respiratory system. Causes burns. Defatting to the skin. Keep away from heat, sparks and flame. Keep away from water. Avoid exposure - obtain special instructions before use. Do not breathe gas. Do not breathe vapor or mist. Do not ingest. Do not get in eyes or on skin or clothing. Contains material that can cause target organ damage. Contains material which may cause cancer, based on animal data. Risk of cancer depends on duration and level of exposure. Use only with adequate ventilation. Keep container tightly closed and sealed until ready for use. Wash thoroughly after handling. : : : : OSHA/HCS status : This material is considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200). 2 . 1/12 9/30/2008. Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax Siliconizing Fluid Hazards identification 2 . Corrosive to eyes. Causes burns. Corrosive to the skin. Causes burns. Toxic in contact with skin. Eyes Skin See toxicological information (section 11) : : Medical conditions aggravated by over- exposure Pre-existing respiratory, skin and digestive disorders and disorders involving any other target organs mentioned in this MSDS as being at risk may be aggravated by over- exposure to this product. : Potential chronic health effects Carcinogenicity : Contains material which may cause cancer, based on animal data. Risk of cancer depends on duration and level of exposure. Mutagenicity : No known significant effects or critical hazards. Teratogenicity : No known significant effects or critical hazards. Developmental effects : No known significant effects or critical hazards. Chronic effects : Contains material that can cause target organ damage. Prolonged or repeated contact can defat the skin and lead to irritation, cracking and/or dermatitis. Fertility effects : No known significant effects or critical hazards. Over-exposure signs/symptoms Ingestion : Adverse symptoms may include the following: stomach pains Skin : Adverse symptoms may include the following: pain or irritation redness dryness cracking blistering may occur Eyes : Adverse symptoms may include the following: pain watering redness Inhalation : Adverse symptoms may include the following: respiratory tract irritation coughing Target organs : Contains material which causes damage to the following organs: kidneys, lungs, liver, upper respiratory tract, skin, central nervous system (CNS), eye, lens or cornea. The preparation is classified as dangerous according to Directive 1999/45/EC and its amendments. Classification Carc. Cat. 3; R40 T; R23/24/25, R48/23 N; R59 R52/53 : Human health hazards : Limited evidence of a carcinogenic effect. Toxic by inhalation, in contact with skin and if swallowed. Toxic: danger of serious damage to health by prolonged exposure through inhalation. Environmental hazards : Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Dangerous for the ozone layer. 2/12 9/30/2008. Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax Siliconizing Fluid Carbon Tetrachloride 56-23-5 80 - 95 Dimethyldichlorosilane 75-78-5 3 - 5 Composition/information on ingredients Name CAS number % United States 3 . There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section. Substance/preparation Preparation : Ingredient name CAS number % Classification EC number Carbon Tetrachloride 56-23-5 80 - 95 200-262-8 Carc. Cat. 3; R40 T; R23/24/25, R48/23 N; R59 R52/53 [1] [2] Dimethyldichlorosilane 75-78-5 3 - 5 200-901-0 F; R11 Xi; R36/37/38 [1] Europe [1] Substance classified with a health or environmental hazard [2] Substance with a workplace exposure limit Occupational exposure limits, if available, are listed in section 8. Get medical attention immediately. Wash out mouth with water. Remove dentures if any. Move exposed person to fresh air. Keep person warm and at rest. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Chemical burns must be treated promptly by a physician. Never give anything by mouth to an unconscious person. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention immediately. Wash skin thoroughly with soap and water or use recognized skin cleanser. Remove contaminated clothing and shoes. Wash contaminated clothing thoroughly with water before removing or wear gloves. Continue to rinse for at least 10 minutes. Chemical burns must be treated promptly by a physician. Wash clothing before reuse. Clean shoes thoroughly before reuse. Get medical attention immediately. Move exposed person to fresh air. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or self- contained breathing apparatus. Keep person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. It may be dangerous to the person providing aid to give mouth-to- mouth resuscitation. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. First aid measures Skin contact Inhalation Ingestion : : : 4 . 3/12 9/30/2008. Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax Siliconizing Fluid First aid measures 4 . Get medical attention immediately. Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Check for and remove any contact lenses. Chemical burns must be treated promptly by a physician. Eye contact : Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training. If it is suspected that fumes are still present, the rescuer should wear an appropriate mask or self-contained breathing apparatus. It may be dangerous to the person providing aid to give mouth-to-mouth resuscitation. Wash contaminated clothing thoroughly with water before removing or wear gloves. See section 11 for more detailed information on health effects and symptoms. Use dry chemical or CO2. Fire-fighting measures Extinguishing media Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. Move containers from fire area if this can be done without risk. Use water spray to keep fire-exposed containers cool. Contact with water liberates toxic, extremely flammable gas. In a fire or if heated, a pressure increase will occur and the container may burst. Runoff to sewer may create fire or explosion hazard. Special protective equipment for fire-fighters Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode. : 5 . Special exposure hazards : Do not use water or foam. Suitable : Not suitable : Hazardous combustion products : Decomposition products may include the following materials: carbon oxides halogenated compounds metal oxide/oxides Flammability of the product : No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Keep away from water. Avoid breathing vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). Stop leak if without risk. Move containers from spill area. Approach release from upwind. Prevent entry into sewers, water courses, basements or confined areas. Avoid allowing the spilled material to get wet or using water to clean up spillages or residues, unless the quantity remaining is very small. Contain and collect spillage with non- combustible, absorbent material e.g. sand, earth, vermiculite or diatomaceous earth and place in container for disposal according to local regulations (see section 13). Use spark-proof tools and explosion-proof equipment. Dispose of via a licensed waste disposal contractor. Contaminated absorbent material may pose the same hazard as the spilled product. Note: see section 1 for emergency contact information and section 13 for waste disposal. Environmental precautions Accidental release measures : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Personal precautions : Large spill : 6 . 4/12 9/30/2008. Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax Siliconizing Fluid Accidental release measures 6 . Stop leak if without risk. Move containers from spill area. Avoid allowing the spilled material to get wet or using water to clean up spillages or residues, unless the quantity remaining is very small. Absorb with an inert material and place in an appropriate waste disposal container. Use spark-proof tools and explosion-proof equipment. Dispose of via a licensed waste disposal contractor. Small spill : Store between the following temperatures: 20 to 25°C (68 to 77°F). Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Keep away from water. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination. Put on appropriate personal protective equipment (see section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Do not get in eyes or on skin or clothing. Do not breathe vapor or mist. Do not ingest. Use only with adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Store and use away from heat, sparks, open flame or any other ignition source. Keep away from water. Empty containers retain product residue and can be hazardous. Do not reuse container. Handling and storage Handling Storage : : 7 . carbon tetrachloride ACGIH TLV (United States, 0/2000). Skin TWA: 5 ppm 8 hour(s). STEL: 10 ppm 15 minute(s). TWA: 2 ppm 8 hour(s). STEL: 63 ppm 15 minute(s). NIOSH (United States, 0/1994). STEL: 2 ppm ACGIH TLV (United States, 1/2008). Skin STEL: 63 mg/m³ 15 minute(s). STEL: 10 ppm 15 minute(s). TWA: 31 mg/m³ 8 hour(s). TWA: 5 ppm 8 hour(s). NIOSH REL (United States, 12/2001). STEL: 12.6 mg/m³ 60 minute(s). STEL: 2 ppm 60 minute(s). OSHA PEL 1989 (United States, 3/1989). TWA: 12.6 mg/m³ 8 hour(s). TWA: 2 ppm 8 hour(s). OSHA PEL Z2 (United States, 11/2006). AMP: 200 ppm 5 minute(s). CEIL: 25 ppm TWA: 10 ppm 8 hour(s). dimethyldichlorosilane AIHA WEEL (United States, 1/2008). CEIL: 2 ppm Exposure controls/personal protection Product name Exposure limits United States 8 . 5/12 9/30/2008. Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax Siliconizing Fluid Exposure controls/personal protection 8 . Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator. Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts. Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product. Personal protection Eyes Skin Respiratory Consult local authorities for acceptable exposure limits. : : : Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. Hands : Engineering measures : Use only with adequate ventilation. Engineering controls may be required to control the primary or secondary risks associated with this product. Use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure to airborne contaminants below any recommended or statutory limits. The engineering controls also need to keep gas, vapor or dust concentrations below any lower explosive limits. Use explosion-proof ventilation equipment. Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location. Recommended monitoring procedures : If this product contains ingredients with exposure limits, personal, workplace atmosphere or biological monitoring may be required to determine the effectiveness of the ventilation or other control measures and/or the necessity to use respiratory protective equipment. Environmental exposure controls : Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels. Europe carbon tetrachloride ACGIH TLV (United States, 0/2000). Skin TWA: 5 ppm 8 hour(s). STEL: 10 ppm 15 minute(s). TWA: 2 ppm 8 hour(s). STEL: 63 ppm 15 minute(s). STEL: 63 mg/m³ 15 minute(s). STEL: 10 ppm 15 minute(s). TWA: 31 mg/m³ 8 hour(s). TWA: 5 ppm 8 hour(s). 6/12 9/30/2008. Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax Siliconizing Fluid Liquid. White to yellowish. Physical and chemical properties Physical state Color : : 9 . The product is stable. Under normal conditions of storage and use, hazardous polymerization will not occur. Reactive or incompatible with the following materials: water Contact with water liberates toxic, extremely flammable gas. Avoid all possible sources of ignition (spark or flame). Do not pressurize, cut, weld, braze, solder, drill, grind or expose containers to heat or sources of ignition. Stability and reactivity Chemical stability Conditions to avoid Incompatible materials Hazardous decomposition products : : : : 10 . Toxicological information United States 11 . Acute toxicity carbon tetrachloride LD Intraperitoneal Rat 0.1 mL/kg - LD50 Dermal Rabbit >20 gm/kg - LD50 Dermal Rat 5070 mg/kg - LD50 Intraperitoneal Rat 1500 uL/kg - LD50 Oral Rat 2350 mg/kg - LDLo Intraperitoneal Rat 3 mL/kg - LDLo Intratracheal Rat 90 mg/kg - TDLo Intraperitoneal Rat 2 mL/kg - TDLo Intraperitoneal Rat 2 mL/kg - TDLo Intraperitoneal Rat 1.5 mL/kg - TDLo Intraperitoneal Rat 0.25 mL/kg - TDLo Intraperitoneal Rat 300 mg/kg - TDLo Intraperitoneal Rat 120 mg/kg - TDLo Intraperitoneal Rat 26 uL/kg - TDLo Intraperitoneal Rat 0.25 mL/kg - TDLo Intraperitoneal Rat 1 mL/kg - TDLo Intravenous Rat 3200 mg/kg - TDLo Intraperitoneal Rat 1 mL/kg - Product/ingredient name Result Species Dose Exposure 7/12 9/30/2008. Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax Siliconizing Fluid Toxicological information 11 . TDLo Oral Rat 1600 mg/kg - TDLo Oral Rat 1600 mg/kg - TDLo Oral Rat 0.25 mL/kg - TDLo Oral Rat 1 gm/kg - TDLo Intraperitoneal Rat 1 mL/kg - TDLo Oral Rat 800 mg/kg - TDLo Oral Rat 800 mg/kg - TDLo Oral Rat 800 mg/kg - TDLo Intraperitoneal Rat 3 mL/kg - TDLo Oral Rat 0.8 mL/kg - TDLo Oral Rat 0.66 mg/kg - TDLo Oral Rat 200 mg/kg - TDLo Oral Rat 8 mg/kg - TDLo Intraperitoneal Rat 1 mL/kg - TDLo Intraperitoneal Rat 1 mL/kg - TDLo Oral Rat 0.25 mL/kg - TDLo Parenteral Rat 1 mL/kg - TDLo Intraperitoneal Rat 1 mL/kg - TDLo Subcutaneous Rat 4000 mg/kg - TDLo Unreported Rat 1 mL/kg - LC50 Inhalation Vapor Rat 46000 mg/m3 6 hours LC50 Inhalation Vapor Rat 8000 ppm 4 hours LC50 Inhalation Vapor Rat 8000 ppm 4 hours dimethyldichlorosilane LD50 Oral Rat 5660 uL/kg - LDLo Intraperitoneal Rat 10 mg/kg - TDLo Dermal Rabbit 100 pph - LC50 Inhalation Vapor Rat 930 ppm 4 hours Conclusion/Summary : Not available. Chronic toxicity Conclusion/Summary : Not available. Carcinogenicity Conclusion/Summary : Not available. Mutagenicity Conclusion/Summary : Not available. Teratogenicity Classification carbon tetrachloride A2 2B B + Possible + dimethyldichlorosilane - - - None. - None. Product/ingredient name ACGIH EPA NIOSH NTP IARC OSHA 8/12 9/30/2008. Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax Siliconizing Fluid Toxicological information 11 . Conclusion/Summary : Not available. Reproductive toxicity Toxic: danger of serious damage to health by prolonged exposure through inhalation. Chronic effects : May cause cancer, based on animal data. Limited evidence of a carcinogenic effect. Risk of cancer depends on duration and level of exposure. Carcinogenicity : No known significant effects or critical hazards. Mutagenicity No known significant effects or critical hazards. Teratogenicity Developmental effects : No known significant effects or critical hazards. Fertility effects : No known significant effects or critical hazards. : : Europe Not available. Conclusion/Summary : Ecological information United States Environmental effects : No known significant effects or critical hazards. 12 . Aquatic ecotoxicity Conclusion/Summary : Not available. Other adverse effects : No known significant effects or critical hazards. The generation of waste should be avoided or minimized wherever possible. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Waste disposal Disposal considerations Disposal should be in accordance with applicable regional, national and local laws and regulations. : 13 . Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION for additional handling information and protection of employees. Hazardous waste : The classification of the product may meet the criteria for a hazardous waste. Transport information 6.1 (4.3) DOT Classification Toxic liquids, water- reactive, n.o.s. (carbon tetrachloride). Marine pollutant (carbon tetrachloride) II Toxic liquids, water- reactive, n.o.s. (carbon tetrachloride) UN3123 IATA-DGR Class 6.1 (4.3) Regulatory information UN number Proper shipping name Classes PG* II UN3123 14 . PG* : Packing group 9/12 9/30/2008. Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax Siliconizing Fluid Water-reactive material Toxic material Corrosive material Carcinogen Target organ effects HCS Classification Regulatory information U.S. Federal regulations WARNING: This product contains a chemical known to the State of California to cause cancer. United States inventory (TSCA 8b): All components are listed or exempted. TSCA 8(d) H and S data reporting: carbon tetrachloride Clean Water Act (CWA) 307: carbon tetrachloride Clean Water Act (CWA) 311: No products were found. Clean Air Act (CAA) 112 accidental release prevention: dimethyldichlorosilane Clean Air Act (CAA) 112 regulated flammable substances: No products were found. Clean Air Act (CAA) 112 regulated toxic substances: dimethyldichlorosilane CEPA Toxic substances: The following components are listed: Tetrachloromethane Canadian ARET: None of the components are listed. Canadian NPRI: The following components are listed: Carbon tetrachloride Alberta Designated Substances: None of the components are listed. Ontario Designated Substances: None of the components are listed. Quebec Designated Substances: None of the components are listed. WHMIS (Canada) Class D-1A: Material causing immediate and serious toxic effects (Very toxic). Class D-2A: Material causing other toxic effects (Very toxic). Class D-2B: Material causing other toxic effects (Toxic). Class E: Corrosive material SARA 302/304/311/312 extremely hazardous substances: dimethyldichlorosilane SARA 302/304 emergency planning and notification: dimethyldichlorosilane SARA 302/304/311/312 hazardous chemicals: carbon tetrachloride; dimethyldichlorosilane SARA 311/312 MSDS distribution - chemical inventory - hazard identification: carbon tetrachloride: Immediate (acute) health hazard, Delayed (chronic) health hazard; dimethyldichlorosilane: Fire hazard, reactive, Immediate (acute) health hazard : : SARA 313 : Canada United States Product name CAS number Concentration SARA 313 notifications must not be detached from the MSDS and any copying and redistribution of the MSDS shall include copying and redistribution of the notice attached to copies of the MSDS subsequently redistributed. carbon tetrachloride Yes. No. 5 µg/day (ingestion) 5 µg/day (inhalation) No. Ingredient name Cancer Reproductive No significant risk level Maximum acceptable dosage level 15 . carbon tetrachloride 56-23-5 80 - 95 dimethyldichlorosilane 75-78-5 3 - 5 carbon tetrachloride 56-23-5 80 - 95 Form R - Reporting requirements Supplier notification : : Canadian lists : California Prop. 65 Canada inventory : Canada inventory: All components are listed or exempted. 10/12 9/30/2008. Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax Siliconizing Fluid Regulatory information 15 . Australia inventory (AICS): All components are listed or exempted. China inventory (IECSC): All components are listed or exempted. Korea inventory (KECI): All components are listed or exempted. Philippines inventory (PICCS): All components are listed or exempted. Japan inventory (ENCS): All components are listed or exempted. International regulations International lists : EU regulations Safety phrases S36/37- Wear suitable protective clothing and gloves. S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). S59- Refer to manufacturer/supplier for information on recovery/recycling. S61- Avoid release to the environment. Refer to special instructions/safety data sheet. R40- Limited evidence of a carcinogenic effect. R23/24/25- Toxic by inhalation, in contact with skin and if swallowed. R48/23- Toxic: danger of serious damage to health by prolonged exposure through inhalation. R59- Dangerous for the ozone layer. R52/53- Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Hazard symbol or symbols Risk phrases : : Toxic, Dangerous for the environment : Other information Hazardous Material Information System (U.S.A.) 3 1 1 * National Fire Protection Association (U.S.A.) Health Flammability Physical hazards WATER-REACTIVE SUBSTANCE. REACTS WITH WATER TO RELEASE FLAMMABLE GAS. REACTS WITH WATER TO RELEASE TOXIC GAS. MAY CAUSE FIRE. MAY BE FATAL IF INHALED. CAUSES RESPIRATORY TRACT, EYE AND SKIN BURNS. HARMFUL IF ABSORBED THROUGH SKIN OR IF SWALLOWED. PROLONGED OR REPEATED CONTACT MAY DRY SKIN AND CAUSE IRRITATION. CONTAINS MATERIAL THAT CAN CAUSE TARGET ORGAN DAMAGE. POSSIBLE CANCER HAZARD - CONTAINS MATERIAL WHICH MAY CAUSE CANCER, BASED ON ANIMAL DATA. Label requirements : : : 16 . The customer is responsible for determining the PPE code for this material. 11/12 9/30/2008. Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax Siliconizing Fluid Other information 16 . 1 1 3 Health Special Instability Flammability Notice to reader To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist. Date of printing Date of issue Date of previous issue Version 9/30/2008. 9/30/2008. 1 No previous validation. : : : : Indicates information that has changed from previously issued version. Full text of R-phrases referred to in sections 2 and 3 - Europe : R11- Highly flammable. R40- Limited evidence of a carcinogenic effect. R23/24/25- Toxic by inhalation, in contact with skin and if swallowed. R48/23- Toxic: danger of serious damage to health by prolonged exposure through inhalation. R36/37/38- Irritating to eyes, respiratory system and skin. R59- Dangerous for the ozone layer. R52/53- Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Full text of classifications referred to in sections 2 and 3 - Europe : F - Highly flammable Carc. Cat. 3 - Carcinogen Category 3 T - Toxic Xi - Irritant N - Dangerous for the environment This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR. 12/12 9/30/2008. Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax