Superfood with Antioxidants
The highest concentrations of anthocyanins and phenolics were observed in fruits harvested in
2012, which is most likely due to the favorable weather conditions (temperature and bright
Also, people with increased cardiovascular risk (i.e., with abdominal obesity, mild
hypercholesterolemia, grade I hypertension) seem to benefit more from the consumption of A.
melanocarpa berry juice and extract. The anti-inflammatory potential of A. melanocarpa juice
was demonstrated in few studies through reduced levels of cytokines (
well as in studies which used patients with cardiovascular disease (
​). Badescu and
​best antioxidant foods
​) demonstrated that the chronic inflammatory reaction related to
diabetes mellitus improves
​ under the action of polyphenols from A.
melanocarpa, specifically through its ability to lower TNF-α and IFN-γ.
One of the underlying therapeutic mechanisms of action of A. melanocarpa is the stimulation of
the endothelial formation of nitric oxide (NO) in coronary arteries (via phosphorilation of
eNOS). Yamane and others (
​best antioxidant fruits
​) showed that in spontaneously hypertensive
rats, a diet containing freeze-dried A. melanocarpa berries significantly reduces SBP along with
a significantly reduced ACE activity at 4 weeks. Overall, these studies showed the potential of
long-term consumption of A. melanocarpa berry juice, although periods of continuous usage
were recommended to be accompanied with a period of abstain. According to Chrubasik et al.
(10), only 13 clinical trials which encompassed various A. melanocarpa products for treatment of
metabolic syndrome, hypercholesterolemia, and type 2 diabetes have been published to date,
while 2 studies had been conducted on healthy participants, and another 3 on other health
Some of the potent bioactive compounds present in the fruits and other parts of the plant were
identified as (−)-epicatec